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Active Pharmaceutical Ingredient

Dow Chemicals R & D Centre

May 2009 (US$130.0M)
Shanghai – China

Three buildings comprising Dow’s 88,000m2 R&D Centre. The larger buildings are the R&D building and the Administration building and the smallest is the Central Utilities Building (CUB).   The R&D and Administration buildings include undercover car park, 64 light laboratories and 1 heavy laboratory, offices, a 700 seat restaurant, Gymnasium, Presidents suite and Badminton court.
The building has an open area through the center with a glass atrium roofprotecting the space.
The CUB building houses the High Voltage and Low Voltage Electrical rooms, Boiler room, Ice chiller tank, Chillers and Fire protection room and holding tank etc.

Pfizer API Pilot Plant

March 2009 (US$27.0M)
Mumbai – India

With a floor area of 5,000m2 over 4 levels this facility produces API (Active Pharmaceutical Ingredients) for animal health and comprises laboratories and clean rooms with HEPA filtration and warehousing, DCS and BMS Control rooms, technical service areas, filter dryers, UPS reactor halls with 9 reactors of which 6 are glass lined and 3 are Hasteloy, transfer panels and drum transfer stations, office and warehousing.
Externally there is a cooling tower, below ground slurry tanks, Organic and Aqueous tanks, and a Blast proof room with Hydrogenation, nitrogen generation plant, Solvent storage tank farm and drum storage area.

Lilly API Plant Retro fit

July 2007
Combined phase 1,2,3
value (US $132.0M)
Guayama – Puerto Rico

Cockram provided the full range of services over the 3 phase project program to retrofit an idle existing API facility. The scope
of projects included  in demolition, rooms retrofit, new equipment installation, new pipe rack, utilities upgrades and instrumentation
modifications. Cockram role commenced with client representative leading the Engineering phase of the project. We also provide
Full Agency CM for phase 1 and 2 of the project. The general scope for Phase 1 included demolition, equipment installation, piping, instrumentation modifications, and architectural modifications around the existing charge room & filter dryer room. The Phase 1 scope also included the necessary tie-ins and planning for future Phase II scope to minimize shut downs and interference when Phase I is in production. Phase II scope includes new structural & architectural alterations and installation of 4 new reactors, filter dryer and conveying & charging systems. To support the increase in capacity for Phase II the following changes will be required: We provided quality assurance and cost controls for the phase 3 project.

Lilly del Caribe Dry Products Compression Suites

August 2005 (US$13.8M)
Carolina – Puerto Rico

Cockram was engaged by Lilly to represent the client and provide Construction Management services for the Encapsulation Suites and Material Movement Corridor for a biotech facility. Our team supervised the construction works using a General Contractor, implemented the safety program, provided scheduling and cost control services and also managed the trade contracts on behalf of Lilly. The Cockram team then continued to provide start-up and validation assistance to the plant team carrying out the Commissioning & Qualification activities.

API Reactor Replacement

Dec 2004 ($5.0M)
Arecibo- Puerto Rico

Cockram have been awarded this fast track, multi staged API facility product expansion project.  Due to the need to introduce new products to the existing facility, the scope consisted of new piping/controls and replacement of two reactors.
The project are run in multi shut down phases and staged engineering release, all to match the existing production capacity and tight product introduction time frame.
The Construction Management  at risk execution consisted of acquiring suitable contractors, arranging tender packages, bid analysis, site supervision, safety management, cost control and contract administration, commissioning/start-up, validation support and site supervision.

Scholle Packaging Facility Fitout

November 2003 (US$0.5M)
Suzhou China

Scholle Industries appointed Cockram to undertake the general construction services for its leased facility. The main scope of Cockram’s services included: general construction services, local project construction permits and approvals, quality controls, program controls, construction management and safety controls, project completion and as-built documentation.